secobarbital will lower the level or effect of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
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Premature infants are specifically liable to the depressant effects of barbiturates. If barbiturates are used for the duration of labor and delivery, resuscitation equipment must be available.
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secobarbital will lower the extent or effect of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
secobarbital will minimize the extent or effect of etravirine by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.
Animal Details. Phenobarbital sodium is carcinogenic in mice and rats right after lifetime administration. In mice, it produced benign and malignant liver cell tumors. In rats, benign liver mobile tumors ended up observed quite late in life.
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Barbiturates are absorbed in various levels following oral or parenteral administration. The salts are more rapidly absorbed than tend to be the acids. The rate of absorption is greater In case the sodium salt is ingested as a dilute Option or taken on an empty tummy.
secobarbital will decrease the extent or effect of doxorubicin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
secobarbital will lessen the level or effect of almotriptan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
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secobarbital and olopatadine intranasal both enhance sedation. Keep away from or Use Alternate Drug. Coadministration will increase threat of CNS depression, which can result in additive impairment of psychomotor overall performance and cause daytime impairment.